Unexplained Weight Loss

Unexplained Weight Loss

What is Unexplained Weight Loss?

Unexplained weight loss refers to a significant and unintended drop in body weight without changes in diet, exercise, or lifestyle. Losing more than 5% of body weight within 6-12 months, especially without trying, could be a sign of an underlying medical condition, often related to the endocrine system.

Common Symptoms Associated with Unexplained Weight Loss

In addition to noticeable weight reduction, patients may experience:

• Increased Hunger or Loss of Appetite – A change in eating habits, either excessive hunger or a loss of interest in food.
• Fatigue & Weakness – Feeling constantly tired or experiencing a decrease in physical strength.
• Excessive Thirst & Frequent Urination – Common symptoms of endocrine disorders like diabetes.
• Changes in Skin & Hair – Dry skin, brittle hair, or hair loss.
• Heart Palpitations – Rapid or irregular heartbeats.
• Digestive Issues – Chronic diarrhea, nausea, or bloating.
• Mood Changes – Anxiety, irritability, or depression.
• Sleep Disturbances – Difficulty falling or staying asleep.
• Muscle or Bone Loss – Reduced muscle mass or bone density leading to weakness.

Possible Endocrine Causes of Unexplained Weight Loss

Several hormonal imbalances can lead to unintended weight loss, including:

• Hyperthyroidism (Overactive Thyroid) – Excess thyroid hormone production speeds up metabolism, leading to rapid weight loss.
• Diabetes (Type 1 & Type 2) – Poor insulin regulation can cause the body to burn fat and muscle for energy.
• Adrenal Disorders (Addison’s Disease) – Insufficient hormone production affecting metabolism and weight stability.
• Pituitary Disorders – Affect hormone regulation, leading to abnormal weight loss.
• Cancer & Paraneoplastic Syndromes – Some tumors can cause metabolic changes leading to weight loss.

When to See a Doctor?

Consult an endocrinologist if you experience unexplained weight loss along with any of the above symptoms. Early diagnosis and management can help address underlying hormonal imbalances and prevent complications.